When Antibiotics Are Ineffective

When Antibiotics Are Ineffective
When Antibiotics Are Ineffective

Video: When Antibiotics Are Ineffective

Отличия серверных жестких дисков от десктопных
Video: When antibiotics are outsmarted | DW Documentary 2023, February
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The main indication for the administration of antibiotics is the presence of a purulent process. But often the use of antibiotics does not give the desired effect. What is the reason for this? There are several reasons pet owners should be aware.

First, with pseudo-inflammation. Sometimes signs of inflammation, such as redness, swelling and soreness in the area of ​​damage, can appear without an infectious origin, for example, with sun and radiation burns. With an infectious process, in addition to a rise in body temperature and an increased content of leukocytes in the blood, purulent discharge is observed.

British blue cat, photo photography
British blue cat, photo photography

Secondly, with the wrong choice of antibiotics… One or another antibiotic acts on a certain type of microorganism. Most often, at the beginning of treatment, antibiotics are selected based on the nature of the disease: the doctor makes a diagnosis, assuming the cause of the disease and prescribes appropriate treatment. But the best way to determine the most effective antibiotic for a disease is to determine the type of microbe that caused the disease by sowing and growing it on nutrient media. Subsequently, its sensitivity to antibiotics is determined. Paper disks soaked in solutions of antibiotics are placed on a solid nutrient medium with a pure culture of a microorganism and the sensitivity of microorganisms is determined by the zone of inhibition of the growth of microorganisms around the disk with a specific antibiotic. The serial dilution method can be used. Those antibioticsthat destroy microbes are effective, and those in the presence of which microbes that continue to multiply are insensitive to this antibiotic. Unfortunately, it is not always possible to conduct laboratory tests, and it takes too long to wait for laboratory test results (7-10 days), which is impossible in cases of rapid development of the disease.

Third, with improper wound care. In cases where there is an abscess, that is, a cavity filled with pus, drugs cannot penetrate the center of this abscess. It must be opened and drained (to remove pus and areas of decayed tissue from it in one way or another). Only then will the effect of the administered antibiotics be observed.

Fourthly, with the wrong administration of antibiotics. Необходимо помнить о том, что путь введения антибиотиков имеет решающее значение в эффективном их применении. Так у животных, у которых наблюдается рвота, потеря сознания и, вообще, тяжелое состояние, введение антибиотиков через пасть не даст никакого эффекта - у них будет нарушено кровообращение в желудочно-кишечном тракте и всасываемости лекарств не будет происходить. В этих случаях антибиотики назначаются внутримышечно или внутривенно. Почти всегда, если антибиотики даются с молоком, об их результативности нечего и говорить - молоко может их нейтрализовать. При лечении мочеполовой системы (заболевания почек, мочевого пузыря и др.) в лечение добавляют препараты, усиливающие кислотность мочи, что способствует лучшему действию антибиотиков на причину, вызвавшую, например, цистит.

And, lastly, on the dose and frequency of administration. Often, the daily dose of antibiotics is underestimated, which leads to ineffective treatment of the animal. When calculating the daily dose of drugs, it is necessary to take into account not only the age of the animal, in which the dose of antibiotics per kilogram of weight will be significantly higher at a young age than in an adult, not only the sex of the animal, but also the severity of the condition, as well as the time of development or aggressiveness of the disease. It is necessary to take into account the interdependent influence of various drugs used in the treatment of a given animal: under the influence of, for example, hormones, antibiotics lose their properties.

© Pilyugin V.V.

Editor: veterinarian, candidate of veterinary sciences V. Aronov - tel.: (812) 923-86-80, mob. +7 (911) 923-86-80.

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